产品货号：
Z25498
中文名称：
ROCK2抗体
英文名称：
Anti-ROCK2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ROCK2 Antibody |
| 指标别名 | KIAA0619;p164 ROCK 2;Rho kinase 2;ROCK2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF |
| 基因名称 | ROCK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human ROCK2 Regulates the assembly of the actin cytoskeleton.Promotes formation of stress fibers and of focal adhesion complexes.Plays a role in smooth muscle contraction. |
| 实际分子量 | 161KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Rho-associated kinase(ROCK),including the ROCK-I and ROCK-II isoforms,is a protein kinase involved in signaling from Rho to actin cytoskeleton.Serine/threonine kinase ROCK II/Rho kinase,which is an isozyme of ROCK I,is one of the targets for the small GTPase Rho.ROCK II regulates the formation of actin stress fibers and focal adhesions,cytokinesis,smooth muscle contraction,and the activation of c-fos serum response element.Sequencing analysis has shown that human ROCK II contains 1388 amino acid residues with a calculated molecular mass of approximately 161kDa.Fluorescence in situ hybridization analysis showed that the human ROCK II gene is located on chromosome 2p24.Thumkeo et al.(2003) concluded that ROCK-II is essential in inhibiting blood coagulation and maintaining blood flow in the endothelium-free labyrinth layer and that loss of ROCK-II leads to thrombus formation,placental dysfunction,intrauterine growth retardation,and fetal death. |
| Uniprot ID | O75116 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
相关搜索：ROCK2抗体，ROCK2多抗，Anti-ROCK2 Antibody